AI is changing how we quantify pain

PainChek was cleared by Australia’s Therapeutic Goods Administration in 2017, and national rollout funding from Canberra helped embed it in hundreds of nursing homes in the country. The system has also won authorization in the UK—where expansion began just before covid-19 started spreading and resumed as lockdowns eased—and in Canada and New Zealand, which are running pilot programs. In the US, it’s currently awaiting an FDA decision. Company‑wide data show “about a 25% drop in anti­psychotic use and, in Scotland, a 42% reduction in falls,” Hoti says.

COURTESY OF PAINCHEK

Orchard Care Homes is one of its early adopters. Baird, then the facility’s director of quality, remembers the pre‑AI routine that was largely done “to prove compliance,” she says.

PainChek added an algorithm to that workflow, and the hybrid approach has paid off. Orchard’s internal study of four care homes tracked monthly pain scores, behavioral incidents, and prescriptions. Within weeks, psychotropic scripts fell and residents’ behavior calmed. The ripple effects went beyond pharmacy tallies. Residents who had skipped meals because of undetected dental pain “began eating again,” Baird notes, and “those who were isolated due to pain began socializing.”

Inside Orchard facilities, a cultural shift is underway. When Baird trained new staff, she likened pain “to measuring blood pressure or oxygen,” she says. “We wouldn’t guess those, so why guess pain?” The analogy lands, but getting people fully on board is still a slog. Some nurses insist their clinical judgment is enough; others balk at another login and audit trail. “The sector has been slow to adopt technology, but it’s changing,” Baird says. That’s helped by the fact that administering a full Abbey Pain Scale takes 20 minutes, while a PainChek scan and checklist take less than five.

Engineers at PainChek are now adapting the code for the very youngest patients. PainChek Infant targets babies under one year, whose grimaces flicker faster than adults’. The algorithm, retrained on neonatal faces, detects six validated facial action units based on the well-established Baby Facial Action Coding System. PainChek Infant is starting limited testing in Australia while the company pursues a separate regulatory pathway.

Skeptics raise familiar red flags about these devices. Facial‑analysis AI has a history of skin‑tone bias, for example. Facial analysis may also misread grimaces stemming from nausea or fear. The tool is only as good as the yes‑or‑no answers that follow the scan; sloppy data entry can skew results in either direction. Results lack the broader clinical and interpersonal context a caregiver is likely to have from interacting with individual patients regularly and understanding their medical history. It’s also possible that clinicians might defer too strongly to the algorithm, over-relying on outside judgment and eroding their own.

If PainChek is approved by the FDA this fall, it will be part of a broader effort to create a system of new pain measurement technology. Other startups are pitching EEG headbands for neuropathic pain, galvanic skin sensors that flag breakthrough cancer pain, and even language models that comb nursing notes for evidence of hidden distress. Still, quantifying pain with an external device could be rife with hidden issues, like bias or inaccuracies, that we will uncover only after significant use.

For Baird, the issue is fairly straightforward nonetheless. “I’ve lived with chronic pain and had a hard time getting people to believe me. [PainChek] would have made a huge difference,” she says. If artificial intelligence can give silent sufferers a numerical voice—and make clinicians listen—then adding one more line to the vital‑sign chart might be worth the screen time.

Deena Mousa is a researcher, grantmaker, and journalist focused on global health, economic development, and scientific and technological progress.

Mousa is employed as lead researcher by Open Philanthropy, a funder and adviser focused on high-impact causes, including global health and the potential risks posed by AI. The research team investigates new causes of focus and is not involved in work related to pain management. Mousa has not been involved with any grants related to pain management, although Open Philanthropy has funded research in this area in the past.